EDG3
Detoxifies foreign compounds (such as carcinogens and harmful metabolites)
(such as Vitamins C and E)
Free radicals — the biggest enemy of your body.
As you age, your body’s glutathione production is rapidly decreasing.
Every day, your cells are being harmed by free radicals. Each cell suffers at least 10,000 hits by free radicals every day, making your cells susceptible to mutation. Some of the contributors of free radicals are polluted air, cigarette smoke, stress, lack of sleep, alcohol, and radiation. Scientist reports show that free radicals are the causal factors in nearly every known disease. Too much of them and you become vulnerable to chronic and serious illnesses, premature ageing, and a weak immune system.
Your body produces glutathione to combat free radicals. However, your body’s glutathione production rapidly declines as you age. Research has shown that low glutathione levels are observed among ill patients and the elderly.
“The amount of antioxidants that you maintain in your body is directly proportional to how well you live,” says Dr Richard Cutler, an anti-ageing researcher from the National Institute of Health.
Studies indicate that the higher the glutathione level in your body, the healthier you are.
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GLUTATHIONE EFFECTS ON THE:
- BRAIN
- HEART
- LIVER
- PANCREAS
- JOINTS
- IMMUNE SYSTEM
- REPRODUCTIVE SYSTEM
- SKIN
Glutathione is scientifically researched to be effective in promoting health in over 99,000 published peer-reviewed studies. It is the master antioxidant because it works inside your cells (intracellular). Unlike other antioxidants such as vitamin C and E, Glutathione works from inside your cell, acting as your cell’s guard that protects your DNA from external attacks. Moreover, normal antioxidants become free radicals when they are used, but glutathione will not. In fact, glutathione even has the unique ability to recycle the used antioxidants and transform them back to unused antioxidants. This will make all the antioxidants in our body work better and longer, creating a powerful antioxidant team in your body.
Click below to expand
Glutathione and Cancer
Cancer is a disease of improper cellular replication due to cell DNA damaged. The immune system destroys cancer cells because it detects this abnormality. However, when too many cancer cells are created, immune system cannot keep up and we end up with cancer. Glutathione protects our DNA from free radical damage and boost up the immunity. Our blueprints remain undamaged and less likely becomes cancerous cells. Strong immune system also protects us from variety of cancers.
Reference – Balendiran, G.K, Dabur, R. and Fraser, D. (2004). The role of glutathione in cancer. Cell Biochem Funct. 22(6), 343-352. Retrieved from https://www.ncbi.nlm.nih.
gov/pubmed/15386533
Glutathione and Diabetes Mellitus
Diabetics have high levels of oxidative stress because when sugar remained in the blood vessels for long time, many free radicals are generated and body’s antioxidant level is not enough to neutralize them. Inflammation leads to insulin resistance which further worsens the complication of diabetes mellitus.
Reference- Sekhar, R.V., et al. (2011). Glutathione synthesis is diminished in patients with uncontrolled diabetes and restored by dietary supplementation with cysteine and glycine. Diabetes Care,34, 162-167. Retrieved from https://www.ncbi.nlm.nih.
gov/pmc/articles/PMC3005481/
Glutathione and Eye Disease
The lens of your eyes is highly concentrated with glutathione. Free radicals are constantly generated in your eyes especially when you’re working in front of your computer, or expose to environmental pollution. Free radicals continuously damage your lens, and accelerate the aging process, leading to dry eyes, cataract, etc. Glutathione protects the eyes from free radical damage, and thereby maintaining healthy vision.
Reference – Giblin, F.J. (2000). Glutathione: a vital lens antioxidant. J Ocul Pharmacol Ther, 16(2), 121-135. Retrieved from https://www.ncbi.nlm.nih.
gov/pubmed/10803423
Glutathione and Alzheimer’s Disease
Brain cells are frequently exposed to many free radicals because it consumes 20% of the oxygen used in the body. Free radicals damage the brain cells, deteriorate your memory and increase your risk of Alzheimer’s, Parkinson, etc. Therefore, glutathione is an important antioxidant to protect the brain and delay the aging process. Studies reported that increasing glutathione is a promising therapeutic strategy to prevent or slow the progression of Alzheimer’s disease.
Reference – Pocernich, C.B. and Butterfield, D.A. (2012). Review: Elevation of glutathione as a therapeutic strategy in Alzheimer disease. Biochimica et Biophysica Acta 1822, 625-630. Retrieved from https://www.ncbi.nlm.nih.
gov/pmc/articles/PMC3277671/
Immune Formulation 200® Amino Acid Blend (Glycine, L-Glutamine, L-Cystine), Selenomethionine, Fibre, Mixed Berries Powder, and Vitamin C
Mix one (1) sachet of EDG3 with 120 ml water, stir well, and drink. Best consumed on an empty stomach, in the morning at least 30 minutes before consuming food (1 hour for best results). Individual needs may vary. If you feel sick or weak, you are recommended to consume two (2) sachets a day – one in the morning and one in the evening.
1. What is EDG3?
EDG3 is a U.S.-patented amino acid blend proven to increase glutathione levels in your body much better than other formulas. EDG3 is the only formula using Cystine, a breakthrough delivery system to guarantee the highest absorption into the cells. EDG3 works to activate Glutathione production in your body, boost your immune system, and protect your cells from the harmful effects of free radicals and toxins.
2. I get my Vitamin C as my antioxidant from fruits and vegetables. Why do I need EDG3?
people do not realise that their daily antioxidant needs cannot be fulfilled by consuming fruits and vegetables alone. Effective antioxidant protection absolutely requires adequate production of the body’s own antioxidant – glutathione. Glutathione is the master of all antioxidants because it works better than other antioxidants to protect your cells against cellular stress.
3. Does EDG3 contain glutathione?
EDG3 does not contain glutathione, but it contains the key building blocks (glycine, glutamine and cystine) for your body to produce glutathione the exact way nature intended. EDG3 is a formula proven to perform better than oral glutathione and other glutathione precursor formulas, owing to its superior delivery system and ingredients.
4. How does EDG3 increase glutathione levels?
Almost all other glutathione products either contain glutathione or contain an incomplete or less effective combination of building blocks, which fail to increase glutathione levels in all cells than the way that EDG3 is able to. Science indicates that all these formulas are not as effective because they are easily oxidised in the digestive system and thus poorly absorbed.
5. What is the difference between Cystine and Cysteine?
Cysteine is the building block of which each cell typically needs more, in order to produce glutathione. The problem is that Cysteine is unstable and, when taken directly, is not easily transported to your cells. The revolutionary transport method used in EDG3 utilises a similar but different molecule called Cystine. The Cystine in EDG3 solves the problem by surviving the journey all the way to your cell walls, entering the cell and then splitting into two cysteine molecules vital for glutathione synthesis to occur in the cell.
6. How long will it take before I see results from using EDG3?
You will notice the first effects of EDG3 after one month of regular use (1 box). The first noticeable effect is usually brighter skin and improved sense of health. After this, you will notice lower incidence of common ailments such as colds and flu, and less severe symptoms when you do fall sick. Long-term, you will enjoy reduced risks of numerous chronic, age-related illnesses.
7. Are there clinical studies to support the claims of EDG3?
There are about 120,000 studies published to support the health benefits of increasing glutathione levels. EDG3 involves a method for increasing glutathione in the body that is U.S.-patented and scientifically proven. For more information, see these references:
Crum, A. (2011). Nutritional and therapeutic compositions and methods to increase bodily glutathione levels. US Patent RE42645E. Originally filed 9 March 2006. Reissued 23 August 2011.
Sinha-Hikim, I., et. al. (2011). A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis. Experimental and Molecular Pathology, Volume 91, Issue 1, Pages 419-428, ISSN 0014-4800. Retrieved from http://dx.doi.org/10.1016/j.yexmp.2011.04.009
8. Are there any known negative side effects of taking EDG3?
EDG3 is all-natural and non-toxic with no added colours, artificial flavours, or preservatives. It is safe to drink even in more than the recommended dose. A small number of people may experience ‘healing crisis’, medically termed 'Herxheimer reaction', our body’s natural response due to active cellular repair, in which one may experience mild flu-like symptoms for a few days.
This just means that the product is actually working on the tissues. You should then continue taking the supplement and drink a lot of water. The healing reaction will automatically disappear a few days later.
9. Does EDG3 meet Good Manufacturing Practices?
Yes, EDG3 meets and exceeds GMP. The safety and purity of all its ingredients have passed independent laboratory testing, auditing, and third-party certification. The most comprehensive quality systems in the industry used. EDG3 has stringent quality control. EDG3 is HACCP certified, Vegan, GMO-free and gluten-free.
Most references can be found at the National Library of Medicine
https://pubmed.ncbi.nlm.nih.
gov/
1. White, Blanaid (2005). Analysis of 8-oxo-7, 8-dihydroGuanine formation and oxidation mediated by Fenton reaction induced DNA oxidative stress. PhD thesis, Dublin City
https://pubmed.ncbi.nlm.nih.
gov/16881006/
2. Montero, D., Tachibana, C., Winther, J.R., Appenzeller-Herzog, C. (2013). Intracellular glutathione pools are heterogeneously concentrated. Redox Biology, 508-513
https://pubmed.ncbi.nlm.nih.
gov/24251119/
3. Lushchak, V.I. (2011). Glutathione homeostasis and functions:Potential targets for medical interventions. J. Amino Acid
https://pubmed.ncbi.nlm.nih.
gov/22500213/
4. Witchi, A., Reddy, S., Stofer, B. and Lauterburg, B.H. (1992). The systemic availability of oral glutathione. Eur J. Clin Pharmacol, 43(6), 667-9
https://pubmed.ncbi.nlm.nih.
gov/1362956/.
5. Amores-Sanchez, M.I., Medina, M.A. (1999). Glutamine, as a precursor of glutathione, and oxidative stress. Mol Genet Metab., 67(2), 100-105
https://pubmed.ncbi.nlm.nih.
gov/10356308/
6. Susanne B Nicholas, Jun Yuan, Amin Aminzadeh, Keith C Norris, Albert Crum, and Nosratola D Vaziri. Salutary effects of a novel oxidative stress modulator on adenine-induced chronic progressive tubulointerstitial nephropathy
https://www.ncbi.nlm.nih.
gov/pmc/articles/PMC3426391/
7. Allan C. Somersall, Gustavo, B. (1999). Breakthrough in Cell-defense. GOLDENeight Publishing.
https://trove.nla.
gov.au/work/5549520?selectedversion=NBD20637648
8. Albert Crum(2007) Overcoming the intracellular synthesis impasse of glutathione – the "master antioxidant" of the immune system. The unique and vital delivery role of cystine/cysteine coupling and the importance of the sulfhydryl (SH) in detoxifying oxyradicals to preserve cell, gene and health. National Conference of the American Chemical Society, Boston, MA.
9. Nicholas SB, Yuan J, Aminzadeh A, Norris KC, Crum A & Vaziri ND (2012) Salutary effects of a novel oxidative stress modulator on adenine-induced chronic progressive tubulointerstitial nephropathy. Am J of Transl Res, vol. 4, no. 3, pp. 257-68.
10. Sinha-Hikim I, Shen R, Kim H, Hikim A, French S, Vaziri N, Crum A & Norris K (2010) Attenuation of oxidative stress and liver pathology by a novel glutathione precursor in a mouse model of dietary steatosis. Endo Rev, USA.
11. SinhaHikim I, Shen R, Kovacheva E, Crum A, Vaziri ND & Norris KC (2010a) Inhibition of apoptotic signalling in sperminetreated vascular smooth muscle cells by a novel glutathione precursor. Cell Biol Int, vol. 34, no. 5, pp. 503-11.
12. Sinha-Hikim I, Shen R, Lee P, Crum A & Norris K (2008) Evaluation of potential compounds in modifying metabolic and cellular response to increased oxidative stress. J Invest Med, vol. 56, no. 1, pp. 103-267.
13. Sinha-Hikim I, Shen R, Paul Lee WN, Crum A, Vaziri ND & Norris KC (2010) Effects of a novel cystine-based glutathione precursor on oxidative stress in vascular smooth muscle cells. Am J Physiol Cell Physiol, vol. 299, no. 3, pp. C638-42.
https://pubmed.ncbi.nlm.nih.
gov/20592243/
14. Sinha-Hikim I, Sinha-Hikim AP, Parveen M, Shen R, Goswami R, Tran P, Crum A & Norris KC (2013) Long-term supplementation with a cystine-based antioxidant delays loss of muscle mass in aging. J Gerontol A Biol Sci Med Sci, vol. 68, no. 7, pp. 749-59.
15. Sinha-Hikim I, Sinha-Hikim AP, Shen R, Kim H, French SW, Vaziri ND, Crum A, Rajavashisth TB & Norris KC (2011) A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. Exp Mol Pathol, vol. 91, no. 1, pp. 419-28.
16. Tareen N, Lee J, Nicholas SB, Martins D, Sinha-Hikim I & Norris KC (2014). Safety and Eficacy of a Novel Oxidative Stress Modulator (OSM). 13th RCMI International Symposium on Health Disparities, San Juan, PR
